Encoding: UTF-8 Package: replicateBE Version: 1.1.3.9000 Date: 2022-05-03 Title: Average Bioequivalence with Expanding Limits (ABEL) Authors@R: c(person(given = "Helmut", family = "Schütz", role = c("aut", "cre"), email = "helmut.schuetz@bebac.at", comment = c(ORCID = "0000-0002-1167-7880")), person(given = "Michael", family = "Tomashevskiy", role = "ctb", email = "mittyright@yandex.ru"), person(given = "Detlew", family = "Labes", role = "ctb", email = "DetlewLabes@gmx.de", comment = c(ORCID = "0000-0003-2169-426X"))) Author: Helmut Schütz [aut, cre] (), Michael Tomashevskiy [ctb], Detlew Labes [ctb] () Maintainer: Helmut Schütz Authors: (2020) Depends: R (>= 3.5.0) Imports: readxl (>= 1.0.0), PowerTOST (>= 1.5.3), lmerTest, nlme, pbkrtest, graphics, grDevices Suggests: knitr, rmarkdown, testthat, devtools Description: Performs comparative bioavailability calculations for Average Bioequivalence with Expanding Limits (ABEL). Implemented are 'Method A' / 'Method B' and the detection of outliers. If the design allows, assessment of the empiric Type I Error and iteratively adjusting alpha to control the consumer risk. Average Bioequivalence - optionally with a tighter (narrow therapeutic index drugs) or wider acceptance range (South Africa: Cmax) - is implemented as well. License: GPL (>=3) LazyData: true VignetteBuilder: knitr URL: https://github.com/Helmut01/replicateBE BugReports: https://github.com/Helmut01/replicateBE/issues Config/pak/sysreqs: cmake make libicu-dev Repository: https://helmut01.r-universe.dev Date/Publication: 2022-05-04 22:08:43 UTC RemoteUrl: https://github.com/helmut01/replicatebe RemoteRef: HEAD RemoteSha: 08d523145bb6a4c44b7e3f0890cf5f6fd4cd2567 NeedsCompilation: no Packaged: 2026-06-18 11:12:24 UTC; root